Advancing the clinical research ecosystem in Africa

Patient and community engagement: Empowering patients and communities to actively participate in the clinical trial process through inclusive engagement, trust-building, and co-creation of research priorities.

Inclusion of under-represented populations: Addressing barriers that limit participation of marginalized groups—such as children, pregnant women, the elderly, and rural populations—to ensure trials generate relevant, equitable evidence.

Innovation in clinical trial design and technology: Promoting the adoption of innovative and fit-for-purpose trial methods—like decentralized and adaptive designs—along with digital tools that enhance trial efficiency and reach.

Streamlined regulatory and ethics oversight: Advancing coordination, harmonization, and reliance mechanisms to accelerate ethical and regulatory approvals without compromising quality or safety.

Regional collaboration and capacity strengthening: Strengthening clinical trial networks, National Regulatory Authorities (NRAs), and ethics committees through regional cooperation, training, and institutional investment to drive sustainable progress.